Which behaviors induce & suppress Autophagy? Can we have too much autophagy? Does autophagy affect cancer and aging? Two research scientists discuss common ideas on autophagy and the science behind them. Nicolas´ channel (Physionic): null Connect with Gil: Facebook: https://www.facebook.com/DrGilCarvalho/ Twitter: https://twitter.com/NutritionMadeS3 Animations: Even Topland @toplandmedia References: 1-https://skeletalmusclejournal.biomedcentral.com/articles/10.1186/s13395-016-0086-6 2-https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541301/ 3-https://www.molbiolcell.org/doi/full/10.1091/mbc.e10-06-0500 4-https://academic.oup.com/nutritionreviews/article/80/3/439/6433113#332225551 5-https://onlinelibrary.wiley.com/doi/abs/10.1111/sms.12945 6-https://www.nature.com/articles/cr2013166 7-https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910616/ 8-https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509423/ IF & CR cause autophagy https://www.sciencedirect.com/science/article/abs/pii/S1568163718301478 9-https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081520/ 10-https://www.mdpi.com/2073-4409/8/2/123 11-https://www.sciencedirect.com/science/article/abs/pii/S0041008X13005759 ox stress 12-https://www.mdpi.com/2072-6694/13/3/533 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319869/ 13-https://pubmed.ncbi.nlm.nih.gov/17018585/ autophagy & cancer effect varies 14-https://www.mdpi.com/2072-6694/13/14/3498 15-https://aacrjournals.org/cancerdiscovery/article/4/7/773/4604 chemotherapy 16-https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242217/ 17-https://www.sciencedirect.com/science/article/pii/S2666149723000063 17-19h fasting 18-https://www.mdpi.com/2072-6643/11/6/1234 18h 19-https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590100/ 72h water fasting 20-https://www.tandfonline.com/doi/abs/10.4161/auto.3636 nematode lifespan 21-https://www.nature.com/articles/s43587-021-00098-4 autophagy decreases w age 22-https://www.sciencedirect.com/science/article/abs/pii/S157096392030090X lysosome w age 23-https://journals.sagepub.com/doi/abs/10.1097/hjr.0b013e32828622d7 exercise & glutathione 24-https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718030/ 72h fasting loss little muscle 25-https://pubmed.ncbi.nlm.nih.gov/37377031/ Disclaimer: The contents of this video are for informational purposes only and are not intended to be medical advice, diagnosis, or treatment, nor to replace medical care. The information presented herein is accurate and conforms to the available scientific evidence to the best of the author's knowledge as of the time of posting. Always seek the advice of your physician or other qualified health provider with any questions regarding any medical condition. Never disregard professional medical advice or delay seeking it because of information contained in Nutrition Made Simple!. #NutritionMadeSimple #GilCarvalho 0:00 Sneak preview 0:40 Intro 1:44 What is autophagy 4:53 Turning Autophagy ON & OFF 6:49 Exercise and autophagy 8:16 Fasting vs calorie restriction 9:08 Triggers of autophagy 10:53 Autophagy and cancer 13:26 Autophagy nuances 16:13 Timing of Autophagy induction 21:19 Humans vs lab animals 24:44 Measuring Autophagy 27:03 Autophagy & Aging 30:48 Autophagy & muscle loss 32:20 Summary & takeaways