Presented By: Prasanth Puthanveetil, PhD
Speaker Biography: Dr. Puthanveetil is currently working an Assistant Professor of Pharmacology at Midwestern University, Illinois, USA. His lab focuses on metabolic signaling specifically targeting cardiovascular diseases. Dr. Puthanveetil completed his undergraduate and master’s program from India in Pharmaceutical Sciences. Then he went on to do a MSc- PhD program in Pharmacology at the University of British Columbia, Vancouver.
Webinar: Unveiling the Therapeutic Potential of Two Sister Flavonoids Using Omics Based Approaches
Webinar Abstract: Globally there has been a constant rise in the population suffering from cardiovascular diseases mostly due to metabolic complications. We have made use of two high throughput omics-based approaches, transcriptomics and metabolomics to understand the pharmacological and toxicological properties of apigenin and chrysin. Both apigenin and chrysin are naturally occurring compounds belonging to the flavonoid family and present in fruits and vegetables, which are a part of our daily dietary regimen. Our work revealed that apigenin and chrysin were able to able to down regulate cholesterol biosynthesis pathway by inhibiting transcripts encoding for enzymes.
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