All references below. Inhalant misuse is well-documented to cause permanent damage to the body. The neurological damage can be acute, and continued misuse will progress to multi-organ damage. Sudden cardiac death is also known to happen with this misuse, along with a variety of additional problems. Music by https://www.youtube.com/channel/UCp7UpJz4wz2ATmv7SV7-l1Q ► https://lifeformed.bandcamp.com/ More music by T4N3 ► https://soundcloud.com/t4n3 More music inspired by R Prince Medicine ►    • Medicine   Some images by Getty Images Toluene Toxic Leukoencephalopathy Image case courtesy of Dr Chee Kok Yoon, Radiopaedia.org, rID: 17082 These cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet. References: Syndromes of toluene sniffing in adults. Ann Intern Med. 1981;94:758-762. Glue-sniffing and distal renal tubular acidosis: sticking to the facts. https://pubmed.ncbi.nlm.nih.gov/1912400/ Laboratory approach for diagnosis of toluene-based inhalant abuse in a clinical setting. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766772/ Neurotoxicity of solvents in brain of glue abusers. https://pubmed.ncbi.nlm.nih.gov/21783541/ Neural basis of inhalant abuse. https://pubmed.ncbi.nlm.nih.gov/9716942/ A rare but serious case of toluene-induced sudden sniffing death. https://www.sciencedirect.com/science/article/pii/S2211558715000953 Hydrocarbon toxicity: A review. https://www.tandfonline.com/doi/full/10.3109/15563650.2014.923904 Inhalant Misuse in children and adolescents. UpToDate. Accessed 28 Mar 2023. Effect of benzene, toluene, xylene on the .. quality of exposed workers. https://pubmed.ncbi.nlm.nih.gov/11601277/ Effects of pH on Potassium: New Explanations for Old Observations. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3231780 THE EFFECT IN HUMANS OF EXTRACELLULAR pH CHANGE ON THE RELATIONSHIP BETWEEN SERUM POTASSIUM CONCENTRATION AND INTRACELLULAR POTASSIUM. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC441665/ MR Imaging of "Spray Heads": Toluene Abuse via Aerosol Paint Inhalation https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8332768/pdf/8237703.pdf Review of toluene action: clinical evidence, animal studies and molecular targets. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211428/ On the mechanism of rhabdomyolysis in potassium depletion. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC292322 The Effects of Toluene on the Central Nervous System https://academic.oup.com/jnen/article/63/1/1/2916394 Goldfrank’s Toxicologic Emergencies. 11th ed.