► Sign up here and try our FREE content: http://lectur.io/freecontentyt ► If you’re an medical educator or faculty member, visit: http://lectur.io/medytb2u ► THIS VIDEO will unravel the intricate world of drugs, starting with the fascinating realm of "beta blockers." 🧪 What exactly does "blocker" mean in this context? Imagine little "keyholes" on the surface of heart cells and other cells, where certain keys like adrenaline fit and induce changes within the cell. 🗝️ One example: adrenaline plugs into these keyholes, resulting in various biochemical changes throughout the body, which can lead to side effects. 💊 Beta blockers, discovered by Dr. James Black in the 1960s, earned him a Nobel Prize in 1988. 🏆 These drugs prove useful by reducing heart rate, blood pressure, and heart contractility. They work by blocking some actions of the autonomic nervous system, particularly the sympathetic nervous system, responsible for the "fight-or-flight" response. ⚙️ The video delves into the intricacies of how beta blockers rebalance the automatic nervous system, mitigating conditions like angina, heart failure, and hypertension. 🩺 Yet, not all beta blockers are created equal; some are more specific for the heart, while others affect both the heart and lungs or even dilate blood vessels. ⚖️ But here's the catch: while beta blockers offer significant benefits, they can also pose risks, especially when it comes to potential complications in other parts of the body. 💡 The lecture navigates through the complexities, elucidating how these drugs can inadvertently exacerbate conditions like asthma or cause lung side effects. 🫁 With a detailed breakdown of cardiovascular effects and indications, the video empowers medical students to understand the multifaceted role of beta blockers in managing conditions like angina, heart failure, and arrhythmias. ⚡ Moreover, it explores how beta blockers revolutionized the treatment landscape for heart failure, challenging conventional wisdom and showcasing their long-term benefits. 🔄 ► RELATED VIDEOS - If you liked this video and need some more information about the subject, you’ll probably want to check the following videos out: https://www.youtube.com/watch?v=8c2EuTMcz_Q https://www.youtube.com/watch?v=r8YPNXB_iu8 https://www.youtube.com/watch?v=eAgwWAlS0io ► LECTURIO Medical is your all-in-one medical school study companion! 💚 With our easy-to-follow videos, exam replicating clinical case questions and our comprehensive medical concept pages you will be best prepared for all your exams. Discover more and try our FREE content: http://lectur.io/freecontentyt Disclaimer: Lecturio offers educational content for healthcare students to prepare for exams and/or to review knowledge gained at a Medical School. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment suggestions. Our resources are strictly for educational purposes. Always consult healthcare professionals for medical concerns. ► THE PROF 👨‍🏫 Your lecturer is Joseph Alpert M.D. He is Professor of Medicine at the Sarver Heart Center as well as Director of Coronary Care and Medical Director of Cardiac Rehabilitation at the University of Arizona. Additionally, he is a member of the most important cardiologic institutions such as the American Heart Association and the European Society of Cardiology. Because of his outstanding teaching proficiency he is board certified in internal medicine and cardiovascular disease and has won many teaching awards such as the George W. Thorn Award for Excellence in Teaching, the William Osler Master Teacher Award, and the Edward Rhodes Stitt Award for Outstanding Teaching. Furthermore, he received the Distinguished Achievement Award from the Clinical Cardiology Council of the American Heart Association and was selected “Gifted Teacher of the Year” in 2004 by the American College of Cardiology. 🩺 ► INSTALL our free Lecturio app iTunes Store: https://app.adjust.com/z21zrf Play Store: https://app.adjust.com/b01fak ► LET’S CONNECT: • Facebook: https://www.facebook.com/lecturio.medical.education.videos • Instagram: https://www.instagram.com/lecturio_medical_videos • Pinterest: https://www.pinterest.de/lecturiomedical • LinkedIn: https://www.linkedin.com/company/lecturio-medical/ #Lecturio #MedStudents Chapters: 0:00 Introduction: What are beta blockers? 01:09 Why are beta blockers useful? 01:27 Beta Blockers History 01:42 Mechanism of action: How do beta blockers work? 05:21 Beta 1 Receptor Sites 06:04 Beta 2 Receptor Sites 06:17 Beta 3 Receptor Sites 06:35 Beta Blockers Responses 07:30 Beta 1 vs. Beta 2 Selectivity 09:42 Beta-Blocking Effects 10:50 Summary of Use of Beta Blockers in Cardiovascular Diseases 12:16 Mechanism of Beta Blockers Benefits in Ischemic Heart Disease 13:57 Antiarrhythmic Effects of Beta Blockers in Heart Failure 16:13 Mechanisms of Beta Blockers in Heart Failure 20:03 Beta Blockers in Hypertension 20:29 Study Smarter with Lecturio