Phage therapy uses viruses called bacteriophages to destroy specific bacteria. Scientists are hopeful that they could become a tool to fight antibiotic-resistant germs. In this video, Patrick Kelly guides you through the history of phage therapy's development. ☠️NONE OF THE INFORMATION IN THIS VIDEO SHOULD BE USED AS MEDICAL ADVICE OR OPINION. IT IS FOR GENERAL EDUCATION AND ENTERTAINMENT☠️ 🔗 L I N K S 🔗 📱Instagram: https://www.instagram.com/patkellyteaches/ 🐦Twitter: https://twitter.com/PatKellyTeaches 💰Patreon: https://www.patreon.com/corporis 🔬Main channel: null 📚My favorite books https://docs.google.com/document/d/1wuG-8EiF2lMbFdEG-9k1qi1d1KZAdGK1o41o7SYed_k/edit?usp=sharing 🔑 P A T R O N S 🔑 Oxytocin Tier: Mike W | Joanne K | Jim C Jr. | Sal F | Jody O | Ansel K Growth Hormone Tier: Dane M | Brendan P | Brandon K | Kathy K | Pia K | Joe B | Mindi F | Ansel K | Michael G | Brian B | Eileen H | Jonathan G | Waffles the Dog | Brian T | Brian H | Michael R | Karen S | Sarah B | Robin B | Jacob S | Hyeon-Seo | Drake W | Pranav M | Paul | Lucy F | Lucie C | Huynhy | elnombre91 | Alcedo | Magmania | Josef K | Kyle K | Dabrick B | Robert M | Kristal C 📜 S O U R C E S 📜 The Good Virus by Tom Ireland https://www.amazon.com/Good-Virus-Amazing-Forgotten-Promise/dp/1324050837?&_encoding=UTF8&tag=corporis-20&linkCode=ur2&linkId=aa68d4d0cf5456aef18c11eebb8a07d0&camp=1789&creative=9325 The Perfect Predator by Stephanie Strathdee https://www.amazon.com/Perfect-Predator-Scientists-Husband-Superbug/dp/0316418110/ref=sr_1_1?crid=39J5FPAXZ35OB&keywords=the+perfect+predator&qid=1706799668&s=books&sprefix=the+perfect+preda%252Cstripbooks%252C212&sr=1-1&_encoding=UTF8&tag=corporis-20&linkCode=ur2&linkId=70fed613c532aa9e78d3aabf42496ea2&camp=1789&creative=9325 Annotated script here: https://www.patreon.com/posts/phage-video-is-97650618 Bacteriophage Therapy of Bacterial Infections: The Rediscovered Frontier (2021) https://www.mdpi.com/1424-8247/14/1/34 Standardized bacteriophage purification for personalized phage therapy (2020) https://www.nature.com/articles/s41596-020-0346-0 Phage Therapy: A Renewed Approach to Combat Antibiotic-Resistant Bacteria (2019) https://www.cell.com/cell-host-microbe/pdf/S1931-3128(19)30052-6.pdf Phage Cocktail Development for Bacteriophage Therapy (2021) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541335/ Hankin paper (1896) https://archive.org/details/annalesdelinstit10inst/page/522/mode/1up?view=theater https://www.tandfonline.com/doi/pdf/10.4161/bact.1.3.16736?needAccess=true A Brief History of Shigella (2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559768/ An Early History of Phage Therapy in the United States (2021) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231696/ Bacteriophage prehistory (2011) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225782/ The virus in the rivers: histories and antibiotic afterlives of the bacteriophage at the sangam in Allahabad (2020) https://royalsocietypublishing.org/doi/full/10.1098/rsnr.2020.0019 Bacteriophage Therapy (2001) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC90351/ The Third Age of Phage (2005) https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.0030182 An invisible microbe that is antagonistic to the dysentery bacillus (1917) by F. d’Herelle — translation of original French https://www.sciencedirect.com/science/article/pii/S0923250807001507?via%3Dihub Le bacteriophage (1921) by D’Herelle https://archive.org/details/lebactriophages00hrgoog/page/n7/mode/2up Bacteriophage and Staph skin infections (1921) https://gallica.bnf.fr/ark:/12148/bpt6k6541609m/f479.item Cholera and Plague in India: The Bacteriophage Inquiry of 1927-1936 https://web.archive.org/web/20170811194935id_/https://sites.ualberta.ca/~pukatzki/labpage/Lab_News/Entries/2010/11/14_Phage_Therapy_files/The%20Bacteriophage%20Inquiry.pdf The Adoption and Survival of Bacteriophage Therapy in the USSR (2018) https://academic.oup.com/jhmas/article/73/4/385/5128730 The prospect for bacteriophage therapy in Western medicine (2003) https://www.nature.com/articles/nrd1111.pdf An interview with Elizabeth Kutter https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041451/ IMAGES Portrait of Steffanie A. Strathdee by Scott Lafee for Triton Magazine. CC-BY-SA 4.0 https://en.wikipedia.org/wiki/Steffanie_A._Strathdee#/media/File:Strathdee_Portrait.png https://creativecommons.org/licenses/by-sa/4.0/ Intralytix Headquarters by Rayford Payne. CC-BY-SA 4.0 https://upload.wikimedia.org/wikipedia/commons/5/5a/Intralytix_Exterior_Spring.jpg https://www.youtube.com/watch?v=qCzCj4gQWLk 💻 C O N T A C T 💻 patkellyteaches [at] gmail.com ⌛T I M E S T A M P S ⌛ 0:00 intro 0:48 What is a Phage 2:00 Ernest Hankin 5:18 Fredrick Twort 6:50 Felix d’Herelle 16:52 Phage Therapy in the Soviet Union 22:19 Phage Therapy in the USA 25:16 Challenges to phage therapy 28:09 Why are people hopeful? #historyofmedicine #medicalhistory