People with Covid-19 often get sick because the body’s inflammatory response to the virus overreacts. To tamp down that inflammation, researchers at the Feinstein Institutes for Medical Research and Cold Spring Harbor Laboratory, turned their sights toward famotidine, the active ingredient in a common over-the-counter heartburn medication with anti-inflammatory potential. On this bonus episode, we speak with the lead researcher of a unique clinical trial testing the safety and efficacy of famotidine for Covid. Tobias Janowitz, MD, PhD, AN Assistant Professor, Cold Spring Harbor Laboratory and adjunct professor at the Feinstein Institutes, shares the results of the study, as well as how the pandemic impacted their approach and led to an early success story for decentralized trials, repurposing medications and the importance of collaborating with other institutions. Read more about the study: https://www.northwell.edu/news/the-latest/famotidine-clinical-trial-shows-reduction-covid-19-symptoms Chapters 0:16 Intro 0:37 Safety, efficacy of famotidine for Covid 1:33 What is famotidine? 3:22 A fully remote trial 4:36 Virtual trial strengths, weaknesses 5:40 Famotidine dosage for heartburn, Covid treatment 7:47 Decentralized clinical trials 9:34 New paradigms, new problems 10:59 A national focus on decentralized trials 11:55 Collaboration supports clinical excellence 13:54 Outro Northwell Health is New York State’s largest health care provider and private employer, with 21 hospitals, 850+ ambulatory facilities, and more than 18,500 affiliated physicians. We care for over two million people annually in the New York metro area and beyond, thanks to philanthropic support from our communities. Our 79,000 employees – 18,900-plus nurses and 4,900 employed doctors, including nearly 4,200 members of Northwell Health Physician Partners – are working to change health care for the better. We’re making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Graduate Nursing and Physician Assistant Studies. For information on our more than 100 medical specialties, visit Northwell.edu. Interested in a career at Northwell Health? Visit http://bit.ly/2Z7iHFL and explore our many opportunities. The Well - https://thewell.northwell.edu/ Facebook – https://www.facebook.com/northwellhealth Twitter - https://www.twitter.com/northwellhealth Instagram - https://www.instagram.com/northwellhealth LinkedIn - https://www.linkedin/northwellhealth