In a series of moderated talks and conversations designed specifically for students, Nobel Prize laureates will discuss what they have learnt from a life in science. With the help of the audience, the three Nobel Prize laureates participating in this forum (Serge Haroche, physics 2012, David MacMillan, chemistry 2021, and May-Britt Moser, physiology or medicine 2014) will address what it takes remain curious and to choose and tackle big questions, how to overcome the many setbacks encountered in research and how to communicate discoveries to colleagues, policy-makers and the wider public.