support the channel: http://patreon.com/acapellascience subscribe: null mp3: https://timblais.bandcamp.com/track/leukocyte In case you missed the series announcement: https://www.youtube.com/watch?v=vy93YaK8Hj4 My main source for this video was the textbook Cellular and Molecular Immunology by Abul Abbas, Andrew Lichtman & Shiv Pillai. I'll do a deep dive livestream for this piece soon and post a link here when I do! A NOTE ABOUT COPYRIGHT: A Capella Science parodies are covered under fair dealing in Canadian law and fair use under American law. Unfortunately for me though, YouTube is mostly governed in practice by agreements between YouTube, the creators, and the record labels. To keep from being sued YouTube gives very generous powers to big labels like EMI, Sony BMG, etc, which include automated copyright claiming and final say in the event of a dispute. I've tried to fight claims in the past but always hit a brick wall, so those videos that are monetized on my channel are monetized as "revenue sharing cover songs". Overall my income from the channel, purely from ads, is about 55 cents per thousand views--normal CPM is anywhere from 2-5 dollars, so I'm making somewhere between 1/4 and 1/10 of normal. Luckily I also have an incredibly generous community, and with the help of my patrons (along with private gigs) I can keep this channel going! ---LYRICS-- Cause I I I got the SARS tonight So watch me ring up my blood cells of white First up Coming through the blood Neutrophil come slow your roll Eat up micro bods Gummed up when your guts explode Hang tight waiting monocyte Hulk out til you're chowing em down Signals from my killer cells And those weak and infected go "blao" This is getting heavy Better get the lymph nodes all ready Got a fever running And these signal cytokines flooding Defense overrun we need to send a sample on Dendritic, you gotta go off so let's go! Cause I I I got the SARS tonight So watch me bring peptides to the meeting site Fly into the lymph node with the details of the bug So I can fight it off by leukocyte Bring a friend, join the crowd Together filling up the node New white lymphocytes Of the thymus and the bone Scatter-gun, million-to-one Which ones are compatible? "Ladies and gentlemen I got the antigen So you can keep your eyes on the ball" This is getting heavy Can we get T's trained already Helping, teaching, gunning Plasma cells with antibods flooding These made optimal We need to save a sample of Archive em, y'all others go off And let's go Cause I I I got the SARS tonight So watch me bring trained cells to the battle site Target a specific set of features of the bug So I can fight it off by leukocyte Slide through the side to find the right site of the fight Fight it leukocyte Fly like a guided viricide bind to the site Fight it leukocyte Target cells exhibiting a feature of the bug So I can fight it off by leukocyte Die for the tribe deny the shock play Try and imbibe a fly-by-night prey Pry, nullify the viral home bay Fight it off leukocyte Spy to provide a vital dossier Vie to supply the binding Y shape Scry, then apply a cytokine aide Fight it off leukocyte Cause I I I got the SARS tonight So watch me bring all guns to the firefight Target tainted tissue with a team to SWAT the bug So I can fight it off by leukocyte Cause I I I got the SARS tonight So watch me bring the fire to the parasite Integrated synergy to seek and squash the bug So I can fight it off by leukocyte Guide what survived to multiply righting the blight Right it leukocyte Time to resign, the high supply cost to requite Bite it leukocyte But I will keep this memory with features of the bug So I can fight it off by leukocyte