Louise Aigrain is a senior staff scientist, working in DNA Pipelines Research and Development group at the Wellcome Trust Sanger Institute. In this film she outline all the process involved in sequencing a DNA sample, from receiving a prepared sample to releasing the assembled data to the scientists. She discusses how to working safely and efficiently in the lab as well as how to track samples and carry out quality control checks. The R & D group develop new and improved methods to sequence DNA samples using a range of different technologies at the Wellcome Trust Sanger Institute. This is one of a series of Life in the lab films providing a more in-depth insight to some of the laboratory processes used by different teams at the Wellcome Trust Sanger Institute. The film has been developed to help support the OCR Cambridge Technical Level 3 in laboratory skills.