Hexagons appear all over the natural world from honeycomb to bubbles, and they even appear in organic chemistry! In this episode of Crash Course Organic Chemistry, we're learning all about cyclohexanes, including how rings pucker to relieve strain, the boat and chair conformations, and how ring flips can switch substituents from axial to equatorial. We'll practice a lot of chair flips, but don't flip an actual chair just yet! Lots of practice is key to understanding organic chemistry's favorite manifestation of the hexagon. Episode Sources: Philip Ball, Why Nature Prefers Hexagons: The geometric rules behind fly eyes, honeycombs and soap bubbles. Nautilus, 2016., Last accessed 1/26/2020. nautil.us/issue/35/boundaries/why-nature-prefers-hexagons References within: Kashyap Vyas, Why is the hexagon everywhere? All about this seemingly common shape. https://interestingengineering.com/why-is-the-hexagon-everywhere-all-about-this-seemingly-common-shape. Last access 1/26/2020. https://www.masterorganicchemistry.com/2014/03/24/cycloalkanes-how-to-calculate-ring-strain/ Series Sources: Brown, W. H., Iverson, B. L., Ansyln, E. V., Foote, C., Organic Chemistry; 8th ed.; Cengage Learning, Boston, 2018. Bruice, P. Y., Organic Chemistry, 7th ed.; Pearson Education, Inc., United States, 2014. Clayden, J., Greeves, N., Warren., S., Organic Chemistry, 2nd ed.; Oxford University Press, New York, 2012. Jones Jr., M.; Fleming, S. A., Organic Chemistry, 5th ed.; W. W. Norton & Company, New York, 2014. Klein., D., Organic Chemistry; 1st ed.; John Wiley & Sons, United States, 2012. Louden M., Organic Chemistry; 5th ed.; Roberts and Company Publishers, Colorado, 2009. McMurry, J., Organic Chemistry, 9th ed.; Cengage Learning, Boston, 2016. Smith, J. G., Organic chemistry; 6th ed.; McGraw-Hill Education, New York, 2020. Wade., L. G., Organic Chemistry; 8th ed.; Pearson Education, Inc., United States, 2013. *** Watch our videos and review your learning with the Crash Course App! Download here for Apple Devices: https://apple.co/3d4eyZo Download here for Android Devices: https://bit.ly/2SrDulJ Crash Course is on Patreon! You can support us directly by signing up at http://www.patreon.com/crashcourse Thanks to the following patrons for their generous monthly contributions that help keep Crash Course free for everyone forever: Catherine Conroy, Leonora Rossé Muñoz, John M Lee, Patty Laqua, Stephen Saar, Eric Prestemon, Sam Buck, Mark Brouwer, William McGraw, Siobhan Sabino, Mark W Billian, Jason Saslow, Jennifer Killen, Jon & Jennifer Smith, Jonathan Zbikowski, Shawn Arnold, Trevin Beattie, Matthew Curls, Khaled El Shalakany, Ian Dundore, Kenneth F Penttinen, Eric Koslow, Timothy J Kwist, Indika Siriwardena, Caleb Weeks, Zhu Junrong, HAIXIANGN/A LIU, Nathan Taylor, Alan Bridgeman, Andrei Krishkevich, Brian Thomas Gossett, SR Foxley, Alexander Thomson, Tom Trval, Justin Zingsheim, Brandon Westmoreland, dorsey, Jessica Wode, Nathan Catchings, Yasenia Cruz, Jirat -- Want to find Crash Course elsewhere on the internet? Facebook - http://www.facebook.com/YouTubeCrashCourse Twitter - http://www.twitter.com/TheCrashCourse Tumblr - http://thecrashcourse.tumblr.com/ Support Crash Course on Patreon: http://patreon.com/crashcourse CC Kids: null