NIH Science in Seconds – a weekly roundup of NIH’s research news. Read more about each of the featured news stories below. Week of May 22, 2023: 1. Scientists have developed a personalized mRNA vaccine approach against a deadly type of pancreatic cancer. While still in early phases of clinical trials, half the participants in a small clinical trial had a strong anti-tumor response to the vaccine. https://bit.ly/3q3Cfg9 2. A large study has provided new insight into the symptoms of Long COVID. The research identified most common symptoms, potential subgroups, and an initial symptom-based scoring system. The findings aim to improve future diagnostics and treatment. https://bit.ly/3OHSutK 3. People with mutations that lead to excessively long chromosome tips, called telomeres, may be at increased risk for a range of cancers. While previous research suggested boosting telomere length might delay age-related illnesses, longer telomeres may carry their own set of risks. https://bit.ly/3Wt2GYV 4. Researchers have found that cells of glioblastoma, a fast-growing brain cancer, steal mitochondria from other cells in the nervous system, which helps the cancer cells grow. This finding could lead to new treatment options. https://bit.ly/3IMTEQL 5. For the first time, researchers have recorded pain-related data from inside the brain of individuals with chronic pain disorders. This finding will help researchers better understand how pain is represented by brain activity and how to modulate that activity to relieve suffering from chronic pain. https://bit.ly/3oGOu1P